Description

2-Bromobenzylzinc Bromide is a versatile organozinc reagent, specifically a benzylzinc halide, widely used in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 2-bromobenzyl moiety into target molecules during the research and development of new drug candidates.
• Negishi Cross-Coupling Reactions: Serves as a critical reagent for coupling with various organic electrophiles (e.g., aryl halides, acid chlorides) to form new C-C bonds with high selectivity.
• Agrochemical Active Ingredient Production: Used in the synthesis of complex molecules for crop protection agents and herbicides.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Utilized in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Custom Chemical Synthesis: Provides a reliable route for contract research organizations (CROs) and fine chemical manufacturers to produce bespoke compounds for clients.

Basic Information

Product Name	2-Bromobenzylzinc Bromide
CAS No.	307496-27-1
Molecular Formula	C7H6Br2Zn
Molecular Weight	313.32 g/mol
Synonyms	(2-Bromobenzyl)zinc bromide; Zinc, bromo(2-bromophenyl)methyl-; (2-Bromophenyl)methylzinc bromide; 2-Bromobenzylzinc bromide solution; Benzene, 1-bromo-2-(bromozinciomethyl)-; Organozinc reagent 2-Bromobenzylzinc bromide
EINECS	Contact for details

Quality Control

Our 2-Bromobenzylzinc Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as concentration (typically supplied as a solution in THF or other solvents), zinc content, and impurity profiles. Our quality commitment aligns with cGMP standards where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. Keep the container tightly sealed in a cool, dry, well-ventilated place. Avoid exposure to air, moisture, and strong oxidizing agents.

Specification

Item	Specification
Appearance (Solution)	Colorless to pale yellow solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identity (NMR)	Conforms to structure
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.