Description

2-Amino-6-Chloro-α-Cyano-3-(Ethoxycarbonyl)-4H-1-Benzopyran-4-Acetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex benzopyran core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory applications.
• Organic Synthesis Research: Serves as a versatile precursor for constructing complex heterocyclic frameworks in academic and industrial R&D laboratories.
• Agrochemical Development: Used in the research and development of new generation pesticides and herbicides due to its bioactive benzopyran structure.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Amino-6-Chloro-α-Cyano-3-(Ethoxycarbonyl)-4H-1-Benzopyran-4-Acetic Acid Ethyl Ester
CAS No.	305834-79-1
Molecular Formula	C₁₇H₁₅ClN₂O₅
Molecular Weight	362.77 g/mol
Synonyms	Ethyl 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetate; 4H-1-Benzopyran-4-acetic acid, 2-amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-, ethyl ester; 2-Amino-6-chloro-4-(ethoxycarbonylmethyl)-3-ethoxycarbonyl-4H-chromene-5-carbonitrile; 6-Chloro-2-amino-3-carbethoxy-4-carbethoxymethyl-5-cyano-4H-chromene; Chromene derivative CAS 305834-79-1
EINECS	Contact for details

Quality Control

Our production of 2-Amino-6-Chloro-α-Cyano-3-(Ethoxycarbonyl)-4H-1-Benzopyran-4-Acetic Acid Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing all critical parameters are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.