Description

3,3-Bis(Hydroxymethyl)Cyclobutan-1-One is a versatile and valuable bifunctional building block featuring both a ketone and two primary alcohol groups within a strained cyclobutane ring. This unique structure makes it a critical intermediate for synthesizing complex molecules in advanced pharmaceutical and fine chemical research. It is particularly sought after by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), specialty polymers, and high-value agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex, strained-ring systems found in novel drug candidates, including potential antiviral and anticancer agents.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polymers with unique thermal and mechanical properties.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides with novel modes of action.
• Ligand and Catalyst Development: The hydroxyl groups provide handles for creating chelating ligands used in asymmetric catalysis.
• Material Science Research: Investigated for creating novel organic frameworks and advanced materials with specific functionalities.
• Academic & Industrial R&D: A valuable tool for methodological studies and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	3,3-Bis(Hydroxymethyl)Cyclobutan-1-One
CAS No.	305819-01-6
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	3,3-Bis(hydroxymethyl)cyclobutanone; 1,1-Bis(hydroxymethyl)cyclobutan-3-one; Cyclobutanone, 3,3-bis(hydroxymethyl)-; 3,3-Di(hydroxymethyl)cyclobutanone; 3-Oxocyclobutane-1,1-dimethanol; 1,1-Cyclobutanedimethanol, 3-oxo-; (3-Oxocyclobutyl)dimethanol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for 3,3-Bis(Hydroxymethyl)Cyclobutan-1-One to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Our standard analytical suite includes HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We can supply material meeting custom purity specifications for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.