Description

4-([4-(Trifluoromethoxy)Anilino]Methyl)-1(2H)-Phthalazinone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct molecular structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key building block in kinase inhibitor synthesis. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology research.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Reagent: Used in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex molecules for biological evaluation.
• Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	4-([4-(Trifluoromethoxy)Anilino]Methyl)-1(2H)-Phthalazinone
CAS No.	305368-11-0
Molecular Formula	C₁₆H₁₂F₃N₃O₂
Molecular Weight	335.28 g/mol
Synonyms	4-[(4-Trifluoromethoxyanilino)methyl]-1(2H)-phthalazinone; 4-[(4-Trifluoromethoxyphenylamino)methyl]phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 4-[[[4-(trifluoromethoxy)phenyl]amino]methyl]-; 4-({[4-(Trifluoromethoxy)phenyl]amino}methyl)-1,2-dihydrophthalazin-1-one; 305368-11-0; 4-(4-Trifluoromethoxy-anilinomethyl)-phthalazin-1(2H)-on
EINECS	Contact for details

Quality Control

Our 4-([4-(Trifluoromethoxy)Anilino]Methyl)-1(2H)-Phthalazinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.