Description

1,2,4-Trioxane,3,6-Dichloro-,(3R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined chlorinated trioxane derivative, serving as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. Its precise stereochemistry and reactive trioxane core make it invaluable for constructing complex molecular architectures with defined spatial orientation. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in antimalarial and antiparasitic drug discovery programs.
• Agrochemical Synthesis: Used as a precursor in the synthesis of advanced, stereoselective pesticides and herbicides, contributing to higher efficacy and environmental specificity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new asymmetric catalytic reactions and chiral auxiliaries.
• Fine Chemical Production: Serves as a specialized intermediate for manufacturing high-value, complex fine chemicals and flavors & fragrances requiring specific stereochemistry.
• Academic & R&D Laboratories: Utilized in fundamental organic chemistry research to study reaction mechanisms, particularly those involving peroxides and stereoselective transformations.
• Material Science Precursor: Potential use in synthesizing specialized monomers or cross-linking agents for polymers with unique properties.

Basic Information

Product Name	1,2,4-Trioxane,3,6-Dichloro-,(3R,6R)-Rel-(9Ci)
CAS No.	304906-12-5
Molecular Formula	C3H4Cl2O3
Molecular Weight	158.97 g/mol
Synonyms	(3R,6R)-3,6-Dichloro-1,2,4-trioxane; rel-(3R,6R)-3,6-Dichloro-1,2,4-trioxane; 3,6-Dichloro-1,2,4-trioxane, (3R,6R)-rel-; 1,2,4-Trioxane, 3,6-dichloro-, (3R,6R)-rel-; Dichlorinated Trioxane Derivative; Chiral Dichlorotrioxane; Artemisinin Derivative Intermediate
EINECS	Contact for details

Quality Control

Our 1,2,4-Trioxane,3,6-Dichloro-,(3R,6R)-Rel-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity, stereochemical purity, and assay. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.