Description

1-[2,6-Dinitro-4-(Trifluoromethyl)Phenyl]-4-Piperidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique aromatic nitro and trifluoromethyl substitution pattern. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and anti-infective research.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the biological activity of the dinitro and trifluoromethyl groups.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and functional materials.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for exploratory chemical synthesis and methodological development.

Basic Information

Product Name	1-[2,6-Dinitro-4-(Trifluoromethyl)Phenyl]-4-Piperidinecarboxylic Acid
CAS No.	303144-43-6
Molecular Formula	C13H12F3N3O6
Molecular Weight	363.25 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[2,6-dinitro-4-(trifluoromethyl)phenyl]-; 1-(2,6-Dinitro-4-trifluoromethylphenyl)piperidine-4-carboxylic acid; 1-[2,6-Dinitro-4-(trifluoromethyl)phenyl]piperidine-4-carboxylic acid; CAS 303144-43-6; 1-(2,6-Dinitro-4-(trifluoromethyl)phenyl)-4-piperidinecarboxylic acid; 4-Carboxy-1-(2,6-dinitro-4-trifluoromethylphenyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-[2,6-Dinitro-4-(Trifluoromethyl)Phenyl]-4-Piperidinecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.