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3-Chloro-6-[(7-Methyl-2,3-Dihydro-1H-Inden-4-Yl)Oxy]Pyridazine CAS NO 303010-12-0
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CAS No.:303010-12-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Chloro-6-[(7-Methyl-2,3-Dihydro-1H-Inden-4-Yl)Oxy]Pyridazine is a high-value, synthetically derived heterocyclic compound featuring a pyridazine core functionalized with chloro and aryloxy substituents. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound's structure is designed to impart specific biological activity and is integral to modern drug discovery pipelines.
Application
- Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
- Agrochemical Research: Serves as a core scaffold for designing and synthesizing new generation herbicides, fungicides, or insecticides with improved efficacy and selectivity.
- Medicinal Chemistry Building Block: Used extensively in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new chemical spaces for biological targets.
- Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for clinical trial material (CTM) and commercial Active Pharmaceutical Ingredient (API) manufacturing.
- Contract Research & Development (CRO/CMO): Supplied to service organizations supporting pharmaceutical and agrochemical companies in their outsourced research and manufacturing activities.
- Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic synthesis, chemical biology, and pharmacology.
Basic Information
| Product Name | 3-Chloro-6-[(7-Methyl-2,3-Dihydro-1H-Inden-4-Yl)Oxy]Pyridazine |
| CAS No. | 303010-12-0 |
| Molecular Formula | C₁₄H₁₃ClN₂O |
| Molecular Weight | 260.72 g/mol |
| Synonyms | 3-Chloro-6-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]pyridazine; 3-Chloro-6-(7-methyl-2,3-dihydro-1H-inden-4-yloxy)pyridazine; 4-[(6-Chloropyridazin-3-yl)oxy]-7-methyl-2,3-dihydro-1H-indene; 7-Methyl-4-[(6-chloro-3-pyridazinyl)oxy]-2,3-dihydro-1H-indene; 303010-12-0; Pyridazine, 3-chloro-6-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]- |
| EINECS | Contact for details |
Quality Control
Every batch of 3-Chloro-6-[(7-Methyl-2,3-Dihydro-1H-Inden-4-Yl)Oxy]Pyridazine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure material consistency and traceability for your regulatory filings. Our quality commitment supports compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up projects.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake. Handle and store in accordance with all applicable local and international regulations.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Any single impurity ≤ 0.5% Total impurities ≤ 1.5% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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