Description

6-(Boc-Amino)-3-Pyridazinecarboxylic Acid CAS NO 301548-08-3 is a high-purity, protected amino acid derivative based on the pyridazine heterocycle, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile, orthogonally protected amine functionality for the controlled construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists engaged in creating novel active pharmaceutical ingredients (APIs), peptide mimetics, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic programs.
• Peptidomimetic Chemistry: Used to incorporate the pyridazine scaffold into peptide backbones, modifying stability, bioavailability, and receptor binding properties.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Employed in the synthesis of specialized chelating ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged or modified molecular probes for studying enzyme function and biological pathways.
• Material Science: A precursor for functionalized polymers and advanced organic materials with specific electronic or photophysical properties.

Basic Information

Product Name	6-(Boc-Amino)-3-Pyridazinecarboxylic Acid
CAS No.	301548-08-3
Molecular Formula	C10H13N3O4
Molecular Weight	239.23 g/mol
Synonyms	3-Pyridazinecarboxylic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-; 6-[(tert-Butoxycarbonyl)amino]pyridazine-3-carboxylic acid; Boc-6-Amino-pyridazine-3-carboxylic acid; 6-(Boc-amino)pyridazine-3-carboxylic acid; tert-Butyl (3-carboxypyridazin-6-yl)carbamate; 6-(N-Boc-amino)-3-pyridazinecarboxylic acid; N-Boc-6-aminopyridazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 6-(Boc-Amino)-3-Pyridazinecarboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) documenting lot-specific results are provided with each shipment. We support custom synthesis and can tailor specifications, including higher purity grades (≥98%, ≥99%), to meet specific research or cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.