Description

3-Methoxyphenylzinc Iodide is a versatile organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for the synthesis of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 3-methoxyphenyl moiety into target molecules during the research and development of new drug candidates.
• Negishi Cross-Coupling Reactions: Used as a nucleophilic coupling partner with various aryl, heteroaryl, or vinyl halides/pseudohalides catalyzed by palladium or nickel complexes.
• Agrochemical Active Ingredient Production: Employed in the synthesis of herbicides, fungicides, and insecticides that incorporate methoxy-substituted aromatic systems.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands or organometallic catalysts used in asymmetric synthesis.
• Materials Science Research: Utilized in the preparation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components or conductive polymers.
• Functionalization of Complex Molecules: Enables the late-stage introduction of the methoxyphenyl group into advanced intermediates, streamlining synthetic routes.

Basic Information

Product Name	3-Methoxyphenylzinc Iodide
CAS No.	300825-30-3
Molecular Formula	C7H7OZnI
Molecular Weight	315.43 g/mol
Synonyms	(3-Methoxyphenyl)zinc iodide; Zinc, (3-methoxyphenyl)-, iodide; m-Methoxyphenylzinc iodide; 3-Methoxybenzenezinc iodide; 3-Methoxyphenylzinc iodide solution
EINECS	Contact for details

Quality Control

Our production of 3-Methoxyphenylzinc Iodide adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by modern analytical techniques, including NMR and titration, to confirm identity, purity, and concentration (typically supplied as a solution in THF or other ethereal solvents). A comprehensive Certificate of Analysis (COA) detailing assay, solvent content, and impurity profile is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, maintain at recommended temperatures (typically 2-8°C for extended storage) and keep away from heat, sparks, and open flames. Use appropriate ventilation and handling procedures for pyrophoric/organometallic reagents.

Specification

Item	Specification
Appearance (Solution)	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (GC/HPLC)	≥ 95% (on an anhydrous basis)
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.