Description

The (R)Schrock-Hoveyda Catalyst is a highly active, chiral molybdenum-based complex designed for asymmetric olefin metathesis reactions. This catalyst is valued for its exceptional selectivity and efficiency in constructing complex chiral molecules, which is critical for producing high-value intermediates. It is an essential tool for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to create enantiomerically pure compounds.

Application

• Asymmetric Ring-Closing Metathesis (ARCM): For the enantioselective synthesis of medium and large-ring heterocycles and carbocycles, crucial in natural product and active pharmaceutical ingredient (API) development.
• Asymmetric Cross Metathesis (ACM): Enables the stereoselective coupling of two different olefins to create chiral building blocks with defined stereocenters.
• Pharmaceutical Intermediate Synthesis: Production of chiral scaffolds for potential drug candidates, including antiviral, anticancer, and neurological agents.
• Agrochemical Research: Synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Creation of chiral flavor and fragrance compounds where specific stereochemistry defines the sensory profile.
• Academic and Industrial R&D: A key reagent for methodological development in organic synthesis and catalysis studies.
• Polymer Science: Exploration of stereoregular polymers via asymmetric acyclic diene metathesis (ADMET) polymerization.

Basic Information

Product Name	(R)Schrock-Hoveyda Catalyst
CAS No.	300344-02-9
Molecular Formula	C31H39MoNO3
Molecular Weight	593.59 g/mol
Synonyms	Molybdenum(VI), [2-[(2,6-Dimethylphenyl)imino]methyl-κN]-2,2-dimethylpropylidene-κC][2,2-dimethyl-2-[(2-methyl-2-propenyl)oxy]propylidene-κC](2,4,6-trimethylphenylimido-κN)-, (R)-; (R)-Molybdenum imido alkylidene complex; (R)-Hoveyda-Grubbs II Catalyst (Note: This is a common misnomer; the Schrock-type catalyst is distinct from Grubbs/Hoveyda ruthenium catalysts); (R)-Schrock Catalyst; Chiral Molybdenum Alkylidene Catalyst; (R)-Mo Catalyst for Asymmetric Metathesis
EINECS	Contact for details

Quality Control

Our (R)Schrock-Hoveyda Catalyst is manufactured under stringent conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including NMR spectroscopy for structural confirmation and purity assessment, and chiral HPLC analysis to verify enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxygen and moisture, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is between 2°C and 8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Orange to brown crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (NMR)	≥ 95%
Enantiomeric Excess (ee)	≥ 99% (by Chiral HPLC)
Solubility	Soluble in common organic solvents (benzene, toluene, THF, dichloromethane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.