Description

6-n-Carbethoxy-3-Chloro-7,8-Dihydro-5H-Pyrido[4,3-C]Pyridazine is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its unique fused pyridopyridazine structure makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in areas requiring complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially for central nervous system (CNS) and cardiovascular targets.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct the core scaffold of potential APIs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Contract Research Organization (CRO) & CDMO Services: Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and reaction methodologies.
• Library Synthesis for High-Throughput Screening: Serves as a building block for creating diverse chemical libraries used in drug discovery campaigns.

Basic Information

Product Name	6-n-Carbethoxy-3-Chloro-7,8-Dihydro-5H-Pyrido[4,3-C]Pyridazine
CAS No.	39715-99-6
Molecular Formula	C₁₀H₁₀ClN₃O₂
Molecular Weight	239.66 g/mol
Synonyms	Ethyl 3-chloro-7,8-dihydro-5H-pyrido[4,3-c]pyridazine-6-carboxylate; 3-Chloro-6-ethoxycarbonyl-7,8-dihydro-5H-pyrido[4,3-c]pyridazine; 6-Carbethoxy-3-chloro-7,8-dihydro-5H-pyrido[4,3-c]pyridazine; 39715-99-6; 3-Chloro-6-(ethoxycarbonyl)-7,8-dihydro-5H-pyrido[4,3-c]pyridazine; Pyrido[4,3-c]pyridazine-6-carboxylic acid, 3-chloro-7,8-dihydro-5H-, ethyl ester
EINECS	Contact for details

Quality Control

Our 6-n-Carbethoxy-3-Chloro-7,8-Dihydro-5H-Pyrido[4,3-C]Pyridazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques like HPLC, GC, and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.