Description

(R)-2-Hydroxy-4-(Methylthio)Butyric Acid is a high-purity, single-enantiomer organic acid that serves as a key chiral intermediate in advanced synthesis. Its value lies in providing the biologically active (R)-configuration essential for efficacy in pharmaceutical and nutraceutical applications. This compound is primarily needed by manufacturers in the pharmaceutical, animal nutrition, and fine chemical industries for producing enantiomerically pure active ingredients and feed additives.

Application

• Pharmaceutical Intermediate: Critical chiral building block for the synthesis of enantiomerically pure drugs, particularly in cardiovascular and metabolic therapies.
• Animal Feed Additive Precursor: Used in the production of methionine hydroxy analogue (HMTBA) supplements, specifically the bioavailable (R)-enantiomer, for poultry and swine nutrition.
• Fine Chemical Synthesis: Employed in asymmetric synthesis and as a starting material for catalysts and ligands in stereoselective reactions.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research.
• Cosmetic Ingredient Synthesis: Potential intermediate for skin-conditioning agents and antioxidants in personal care formulations.

Basic Information

Product Name	(R)-2-Hydroxy-4-(Methylthio)Butyric Acid
CAS No.	39638-34-1
Molecular Formula	C5H10O3S
Molecular Weight	150.20 g/mol
Synonyms	(R)-HMTBA; (R)-2-Hydroxy-4-(methylthio)butanoic acid; (R)-2-Hydroxy-4-methylthiobutanoic acid; D-2-Hydroxy-4-(methylthio)butyric acid; (R)-Methionine hydroxy analogue; (R)-Alimet; (2R)-2-Hydroxy-4-(methylsulfanyl)butanoic acid; (R)-2-Hydroxy-4-(methylmercapto)butyric acid
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxy-4-(Methylthio)Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure compliance with exacting standards for pharmaceutical and feed-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.