Description

p-Nitrobenzyl Mesylate is a versatile chemical intermediate and protecting group reagent of significant importance in synthetic organic chemistry. Its primary value lies in its role as a precursor for the synthesis of more complex molecules, particularly in the development of pharmaceuticals and advanced materials. This compound is essential for research chemists and process development scientists working in pharmaceutical R&D, agrochemical production, and fine chemical manufacturing who require high-purity building blocks for complex syntheses.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing nitrobenzyl or protected alcohol functionalities.
• Protecting Group Reagent: Used to protect hydroxyl groups during multi-step organic synthesis, with the p-nitrobenzyl group being cleavable under specific conditions.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides, fungicides, and other crop protection agents.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other specialty chemicals requiring the nitrobenzyl moiety.
• Research & Development: Critical reagent in academic and industrial laboratories for method development and exploring new synthetic pathways.
• Peptide Chemistry: Can be employed in the synthesis and modification of peptides where temporary protection of side chains is necessary.

Basic Information

Product Name	p-Nitrobenzyl Mesylate
CAS No.	39628-94-9
Molecular Formula	C8H9NO5S
Molecular Weight	231.22 g/mol
Synonyms	4-Nitrobenzyl Methanesulfonate; p-Nitrobenzyl Methanesulfonate; 1-(Methylsulfonyloxy)methyl-4-nitrobenzene; 4-Nitrobenzyl Methylsulfonate; Methanesulfonic Acid 4-Nitrobenzyl Ester; (4-Nitrobenzyl) Methanesulfonate; p-Nitrobenzyl Methanesulphonate; p-Nitrobenzyl Mesylate
EINECS	Contact for details

Quality Control

Our p-Nitrobenzyl Mesylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We are committed to meeting the stringent requirements of our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.