Description

(-)-4-Hydroxy-α-Oxobenzeneacetic Acid 1-[2,3-Dihydro-7-Oxo-7H-Furo[3,2-G][1]Benzopyran-2-Yl]-1-Methylethyl Ester is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of optically active pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Employed as a starting material or advanced intermediate in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials where precise molecular configuration is essential.
• Agrochemical Research: Serves as a precursor in the development of new, stereospecific agrochemicals such as herbicides or plant growth regulators.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, catalysis, and process chemistry within university and corporate research laboratories.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in chromatographic analysis of related compounds.

Basic Information

Product Name	(-)-4-Hydroxy-α-Oxobenzeneacetic Acid 1-[2,3-Dihydro-7-Oxo-7H-Furo[3,2-G][1]Benzopyran-2-Yl]-1-Methylethyl Ester
CAS No.	39380-09-1
Molecular Formula	C22H18O7
Molecular Weight	394.38 g/mol
Synonyms	(-)-4-Hydroxymandelic Acid 1-(2,3-Dihydro-7-oxo-7H-furo[3,2-g]chromen-2-yl)-1-methylethyl Ester; (S)-4-Hydroxy-α-oxobenzeneacetic Acid 1-(2,3-Dihydro-7-oxo-7H-furo[3,2-g]chromen-2-yl)-1-methylethyl Ester; 2,3-Dihydro-7-oxo-7H-furo[3,2-g]chromen-2-yl Isopropyl 4-Hydroxymandelate; 39380-09-1; Furo[3,2-g]chromene Derivative; Chiral Furocoumarin Ester; Optically Active Benzopyran Ester
EINECS	Contact for details

Quality Control

Our (-)-4-Hydroxy-α-Oxobenzeneacetic Acid 1-[2,3-Dihydro-7-Oxo-7H-Furo[3,2-G][1]Benzopyran-2-Yl]-1-Methylethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure consistent enantiomeric excess and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.