Description

n-Chloro-2-Methyl-n-[3-(Trifluoromethyl)Phenyl]Propionamide is a specialized organic compound featuring a trifluoromethylphenyl group and a chloro-substituted amide structure. This molecular architecture makes it a valuable intermediate in advanced synthetic chemistry, particularly for the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Specialty Chemical Manufacturing: Employed in the production of performance chemicals, such as liquid crystal materials or advanced polymer modifiers.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for use in client-specific, multi-step synthetic routes under cGMP conditions where applicable.

Basic Information

Product Name	n-Chloro-2-Methyl-n-[3-(Trifluoromethyl)Phenyl]Propionamide
CAS No.	39240-97-6
Molecular Formula	C11H11ClF3NO
Molecular Weight	265.66 g/mol
Synonyms	N-Chloro-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide; 2-Methyl-N-(3-trifluoromethylphenyl)propionamide, N-chloro derivative; α-Chloro-N-(3-trifluoromethylphenyl)isobutyramide; 39240-97-6; N-Chloro-α-methyl-3-(trifluoromethyl)hydrocinnamamide; Propanamide, N-chloro-2-methyl-N-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our n-Chloro-2-Methyl-n-[3-(Trifluoromethyl)Phenyl]Propionamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.