Description

2-Chloro-3-(Trifluoromethyl)Benzylamine is a high-value, multi-functional aromatic amine building block characterized by its unique trifluoromethyl and chloro substituents. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts critical properties like metabolic stability and lipophilicity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for CNS agents, anti-inflammatories, and kinase inhibitors.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring structure-activity relationships (SAR) and novel organic reactions.
• Fluorine Chemistry Building Block: Valued for introducing the trifluoromethyl moiety into complex molecules, a common strategy in modern medicinal chemistry.

Basic Information

Product Name	2-Chloro-3-(Trifluoromethyl)Benzylamine
CAS No.	39226-96-5
Molecular Formula	C8H7ClF3N
Molecular Weight	209.60 g/mol
Synonyms	(2-Chloro-3-(trifluoromethyl)phenyl)methanamine; 1-(Aminomethyl)-2-chloro-3-(trifluoromethyl)benzene; α-Amino-2-chloro-α,α,α-trifluoro-m-xylene; 2-Chloro-α,α,α-trifluoro-m-toluidine; 2-Chloro-3-trifluoromethylbenzylamine; 2-Chloro-α,α,α-trifluoro-m-tolylamine; Benzylamine, 2-chloro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Trifluoromethyl)Benzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.