Description

4-(4-Chlorophenyl)-3-Butyn-2-One is a versatile and high-purity organic building block characterized by its acetylene and ketone functional groups attached to a chlorinated aromatic ring. This unique structure makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial chemistry. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for constructing complex heterocyclic and aryl-alkyne scaffolds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging the chlorophenyl moiety for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, liquid crystals, and polymers where conjugated systems are required.
• Chemical Research & Development: Employed in organic synthesis for cross-coupling reactions (e.g., Sonogashira) and as a building block for more complex ketone and alkyne derivatives.
• Fine Chemical Production: Integral in the custom synthesis of specialty chemicals, dyes, and pigments.

Basic Information

Product Name	4-(4-Chlorophenyl)-3-Butyn-2-One
CAS No.	39180-26-2
Molecular Formula	C10H7ClO
Molecular Weight	178.61 g/mol
Synonyms	1-(4-Chlorophenyl)-2-propyn-1-one; 4-Chlorophenyl ethynyl ketone; 3-Butyn-2-one, 4-(4-chlorophenyl)-; p-Chlorophenylpropiolyl ketone; 4'-Chlorophenylpropiolyl ketone; 2-Propyn-1-one, 1-(4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)-3-Butyn-2-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.