Description

trans-1-Iodo-1-Octen-3-One is a high-purity, iodinated α,β-unsaturated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive vinyl iodide and an enone moiety, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and Michael additions.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its reactivity to introduce complex side chains.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its polymerizable enone group and halogen handle.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugation reagents where the iodine atom can be used for further functionalization or radiolabeling.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, particularly in studies involving halogenated olefins and conjugate addition reactions.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrance, flavor, and other high-value specialty chemicals.

Basic Information

Product Name	trans-1-Iodo-1-Octen-3-One
CAS No.	39178-64-8
Molecular Formula	C8H13IO
Molecular Weight	252.09 g/mol
Synonyms	(E)-1-Iodo-1-octen-3-one; trans-1-Iodo-1-octen-3-one; 1-Iodo-1-octen-3-one (E)-; (E)-3-Octen-1-one, 1-iodo-; 1-Iodo-1-octen-3-one; 1-Iodo-3-oxo-1-octene; (E)-1-Iodo-3-oxo-1-octene; 3-Octen-1-one, 1-iodo-, (E)-
EINECS	Contact for details

Quality Control

Our trans-1-Iodo-1-Octen-3-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	Clear, pale yellow to amber liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isomeric Purity (GC/HPLC)	≥ 98.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.