Description

4-(tert-Butyl)-2-Iodophenol is a halogenated phenolic compound featuring a bulky tert-butyl group, which significantly influences its steric and electronic properties. This unique structure makes it a valuable advanced intermediate for synthesizing complex molecules in research and industrial chemistry. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in ligand synthesis, material science, and as a building block for active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered phenolic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators where the iodophenol structure is integral.
• Ligand & Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Polymer & Material Science: Acts as a monomer or functionalization agent for producing high-performance polymers and advanced materials.
• Organic Synthesis & Research: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Heck) and introducing the iodophenol functional group into target molecules.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex dyes and organic pigments.

Basic Information

Item	Details
Product Name	4-(tert-Butyl)-2-Iodophenol
CAS No.	38941-98-9
Molecular Formula	C10H13IO
Molecular Weight	276.12 g/mol
Synonyms	2-Iodo-4-tert-butylphenol; 4-tert-Butyl-2-iodophenol; p-tert-Butyl-o-iodophenol; 1-Hydroxy-4-tert-butyl-2-iodobenzene; 2-Hydroxy-5-tert-butyl-1-iodobenzene; Phenol, 4-(1,1-dimethylethyl)-2-iodo-; 4-(1,1-Dimethylethyl)-2-iodophenol
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyl)-2-Iodophenol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for cGMP and research-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.