Description

(1R)-(+)-Nopinone is a high-purity, chiral bicyclic ketone of significant interest in organic synthesis. Its defined stereochemistry and unique structural framework make it a valuable building block for the creation of complex, optically active molecules. This compound is primarily sought after by research institutions and fine chemical manufacturers in the pharmaceutical and fragrance industries for use as a key chiral intermediate or a starting material for terpene-derived compounds.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Serves as a precursor for the development of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Fragrance and Flavor Chemistry: Used in the research and synthesis of novel terpenoid-based aroma compounds and flavors.
• Asymmetric Catalyst Ligand Synthesis: Acts as a starting material for the preparation of chiral ligands used in enantioselective catalysis.
• Natural Product Synthesis: A key building block in the laboratory synthesis of complex natural products with pinane or related skeletons.
• Organic Chemistry Research: Employed in methodological studies and the exploration of new synthetic routes involving bicyclic systems.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with unique optical or physical properties.

Basic Information

Product Name	(1R)-(+)-Nopinone
CAS No.	38651-65-9
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	(+)-Nopinone; (1R,5R)-6,6-Dimethylbicyclo[3.1.1]heptan-2-one; d-Nopinone; (1R)-(+)-6,6-Dimethyl-2-bicyclo[3.1.1]heptanone; (1R,5R)-(-)-Nopinone (common misnomer for the (+)-enantiomer); Bicyclo[3.1.1]heptan-2-one, 6,6-dimethyl-, (1R,5R)-; (+)-2-Pinanone
EINECS	Contact for details

Quality Control

Our (1R)-(+)-Nopinone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific optical rotation to meet rigorous research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 98.0% e.e.
Specific Optical Rotation [α]	+20° to +24° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.