Description

(5E,8E,11E,14E)-5,8,11,14-Icosatetraenoic Acid Methyl Ester is a high-purity methyl ester derivative of arachidonic acid, a key polyunsaturated fatty acid. This compound serves as a critical intermediate and reference standard in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the life sciences, nutraceutical, and pharmaceutical industries who require precise, well-characterized lipid molecules for metabolic studies, analytical method development, and the synthesis of bioactive compounds.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for calibrating analytical instruments like GC-MS and HPLC in lipidomics and metabolomics studies.
• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the production of eicosanoids, prostaglandins, and other bioactive lipid mediators.
• Nutritional Science: Employed in research investigating the metabolism, absorption, and biological effects of ω-6 fatty acids and their esters.
• Cell Culture & In Vitro Studies: Used to supplement media in studies focusing on cell signaling pathways, inflammation, and membrane fluidity.
• Analytical Method Development: Acts as a critical standard for developing and validating assays to quantify arachidonic acid and its derivatives in complex matrices.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations targeting skin barrier function and inflammatory responses.

Basic Information

Product Name	(5E,8E,11E,14E)-5,8,11,14-Icosatetraenoic Acid Methyl Ester
CAS No.	38575-18-7
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	Arachidonic Acid Methyl Ester; Methyl Arachidonate; Methyl (5Z,8Z,11Z,14Z)-Icosatetraenoate; Methyl all-cis-5,8,11,14-Eicosatetraenoate; 5,8,11,14-Eicosatetraenoic Acid, Methyl Ester; AA Methyl Ester; 20:4(n-6) Methyl Ester
EINECS	Contact for details

Quality Control

Our (5E,8E,11E,14E)-5,8,11,14-Icosatetraenoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays (HPLC, GC) and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided and traceable to relevant in-house standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from heat and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Isomeric Purity (GC)	≥ 99.0% (all-cis 5,8,11,14)
Peroxide Value	< 5.0 mEq/kg
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.