Description

Ethanone, 2-Chloro-1-(2-Pyrrolidinyl)-, (S)- (9Ci) is a chiral, high-purity chemical intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Asymmetric Synthesis: Utilized as a precursor or reagent in stereoselective chemical reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a building block in the synthesis of novel, chiral agrochemicals and pesticides.
• Academic & Industrial R&D: Employed in chemical research laboratories for methodological development and the exploration of new synthetic pathways.
• Fine Chemical Production: Used in the manufacture of specialty and custom fine chemicals where precise stereochemistry is required.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(2-Pyrrolidinyl)-, (S)- (9Ci)
CAS No.	38491-75-7
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	(S)-2-Chloro-1-(2-pyrrolidinyl)ethanone; (S)-2-Chloro-1-(pyrrolidin-2-yl)ethanone; L-Proline, 1-(chloroacetyl)-; 1-(Chloroacetyl)-L-proline; (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxylic acid (precursor form); 2-Chloro-1-((S)-pyrrolidin-2-yl)ethanone; A chiral chloroacetyl pyrrolidine derivative.
EINECS	Contact for details

Quality Control

We supply Ethanone, 2-Chloro-1-(2-Pyrrolidinyl)-, (S)- (9Ci) in high-purity grades suitable for research and development. Our quality assurance process includes rigorous analytical testing to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), enantiomeric excess, and impurity profile is provided with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.