Description

Daidzein-7-o-Glucuronide is a major conjugated metabolite of the soy isoflavone daidzein, formed via phase II metabolism. This compound is of significant interest for its role in bioavailability studies and as a reference standard for pharmacokinetic and metabolic research. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories focused on nutraceutical development, drug metabolism, and clinical diagnostics.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quantitative analysis in drug metabolism and pharmacokinetic (DMPK) studies.
• Biomedical Research: Serves as a critical metabolite in in vitro and in vivo studies investigating the bioavailability, absorption, and excretion pathways of daidzein and other isoflavones.
• Clinical Diagnostics: Employed in the development and calibration of assays (e.g., LC-MS/MS) to measure isoflavone metabolite levels in human plasma, serum, or urine for nutritional and epidemiological studies.
• Nutraceutical & Functional Food Analysis: Acts as an analytical standard for quality control and potency verification in soy-based dietary supplements and fortified food products.
• Enzyme Activity Assays: Used as a substrate or product in studies of UDP-glucuronosyltransferase (UGT) enzyme activity and inhibition.

Basic Information

Product Name	Daidzein-7-o-Glucuronide
CAS No.	38482-80-3
Molecular Formula	C21H18O11
Molecular Weight	446.36 g/mol
Synonyms	Daidzein 7-O-β-D-Glucuronide; Daidzein-7-glucuronide; 7-O-Glucuronyl daidzein; 4',7-Dihydroxyisoflavone 7-glucuronide; Daidzein 7-glucuronide; 7-Glucuronide daidzein; Daidzein 7-O-glucuronide
EINECS	Contact for details

Quality Control

Our Daidzein-7-o-Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed chromatograms and full traceability. The product is suitable for use as a pharmaceutical reference standard and meets the rigorous requirements of research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider keeping the product at -20°C under inert atmosphere. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.