Description

1,4-Dichloro-2-Ethynyl-Benzene is a high-purity halogenated aromatic alkyne building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chlorine substituents and an ethynyl group, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and advanced organic electronic materials.
• Organic Synthesis Building Block: Employed in Sonogashira coupling, click chemistry, and other cross-coupling reactions to introduce ethynyl and aryl chloride functionalities.
• Ligand and Catalyst Development: Utilized for constructing complex ligand frameworks in coordination chemistry and catalysis research.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D laboratories exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	1,4-Dichloro-2-Ethynyl-Benzene
CAS No.	38417-89-9
Molecular Formula	C8H4Cl2
Molecular Weight	171.02 g/mol
Synonyms	2-Ethynyl-1,4-dichlorobenzene; 1,4-Dichloro-2-ethynylbenzene; 2,5-Dichlorophenylacetylene; 2-Ethynyl-p-dichlorobenzene; 1,4-Dichloro-2-ethynyl-benzene; (2,5-Dichlorophenyl)acetylene; p-Dichloroethynylbenzene
EINECS	Contact for details

Quality Control

Our 1,4-Dichloro-2-Ethynyl-Benzene is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.