Description

Naringenin Trimethyl Ether CAS NO 38302-15-7 is a chemically modified derivative of the natural flavonoid naringenin, characterized by the methylation of its three phenolic hydroxyl groups. This modification enhances its lipophilicity and metabolic stability, making it a valuable intermediate for advanced research and development. This compound is primarily sought by the pharmaceutical, nutraceutical, and fine chemical industries for its utility in synthesizing novel bioactive molecules and as a reference standard in analytical studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting metabolic and inflammatory pathways.
• Biochemical Research: Used as a reference standard and probe in studies investigating flavonoid metabolism, bioavailability, and structure-activity relationships (SAR).
• Nutraceutical Development: Serves as a precursor or model compound for developing enhanced bioavailable flavonoid formulations.
• Fine Chemical Synthesis: An important intermediate in organic synthesis for creating specialized chemicals with tailored properties.
• Cosmetic Science: Investigated for potential use in premium skincare formulations due to its modified stability profile.

Basic Information

Product Name	Naringenin Trimethyl Ether
CAS No.	38302-15-7
Molecular Formula	C18H18O5
Molecular Weight	314.33 g/mol
Synonyms	5,7-Dihydroxy-2-(4-hydroxyphenyl)-3,4,8-trimethyl-4H-1-benzopyran-4-one; 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one Trimethyl Ether; 4',5,7-Trihydroxyflavanone Trimethyl Ether; Naringenin 4',5,7-Trimethyl Ether; 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Trimethyl Ether; Naringenin 3',5,7-Trimethyl Ether (common misnomer); Flavokawin B (related compound, check specific isomer)
EINECS	Contact for details

Quality Control

Our Naringenin Trimethyl Ether is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets precise specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.