Description

α-Chloroacetophenone 2,4-Dinitrophenyl Hydrazone is a specialized organic derivative of 2,4-dinitrophenylhydrazine (DNPH), primarily utilized as a key analytical reagent and synthetic intermediate. This compound matters for its critical role in the derivatization and subsequent detection of carbonyl compounds, including ketones and aldehydes, via high-performance liquid chromatography (HPLC) or spectrophotometry. It is essential for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and chemical manufacturing sectors who require precise analytical methods.

Application

• Analytical Chemistry Reagent: Used as a derivatizing agent for the qualitative and quantitative analysis of carbonyl compounds (aldehydes and ketones) in complex matrices.
• Pharmaceutical Impurity Profiling: Employed in the detection and quantification of trace carbonyl-containing impurities or degradation products in active pharmaceutical ingredients (APIs) and drug formulations.
• Environmental Testing: Applied in air and water quality monitoring to analyze formaldehyde and other volatile organic carbonyl pollutants.
• Chemical Synthesis Intermediate: Serves as a building block in organic synthesis for the preparation of more complex hydrazone derivatives with potential biological activity.
• Food and Beverage Analysis: Utilized in testing for carbonyl compounds that can indicate spoilage, oxidation, or fermentation processes.
• Material Science Research: Acts as a reagent in polymer chemistry to study degradation products or to functionalize surfaces.

Basic Information

Product Name	α-Chloroacetophenone 2,4-Dinitrophenyl Hydrazone
CAS No.	38293-71-9
Molecular Formula	C14H11ClN4O4
Molecular Weight	334.72 g/mol
Synonyms	2-Chloroacetophenone 2,4-dinitrophenylhydrazone; 1-(2-Chloroacetyl)benzene 2,4-dinitrophenylhydrazone; Phenacyl chloride 2,4-DNPH derivative; α-Chloroacetophenone DNPH; 2,4-Dinitrophenylhydrazone of 2'-Chloroacetophenone; (2-Chloro-1-phenylethan-1-one) (2,4-dinitrophenyl)hydrazone; DNPH derivative of 2-Chloroacetophenone
EINECS	Contact for details

Quality Control

Our α-Chloroacetophenone 2,4-Dinitrophenyl Hydrazone is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency suitable for sensitive analytical applications. Each lot undergoes rigorous testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.