Description

8-Methyl-4-oxo-4H-chromene-2-carboxylic acid is a high-purity chromone derivative, a versatile heterocyclic building block prized for its structural framework. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting inflammation, cancer, and CNS disorders.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and plant growth regulators leveraging the chromone scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer components in electronic displays.
• Fluorescent Dyes and Probes: Acts as a core structure for developing sensitive chemical sensors and bio-imaging agents.
• Material Science Research: Employed in the synthesis of novel polymers, ligands for metal-organic frameworks (MOFs), and advanced organic materials.
• Academic & Industrial R&D: A fundamental building block for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	8-Methyl-4-oxo-4H-chromene-2-carboxylic acid
CAS No.	38243-78-6
Molecular Formula	C11H8O4
Molecular Weight	204.18 g/mol
Synonyms	8-Methyl-4-oxo-4H-1-benzopyran-2-carboxylic acid; 2-Carboxy-8-methyl-4H-1-benzopyran-4-one; 8-Methylchromone-2-carboxylic acid; 8-Methyl-4-oxochromene-2-carboxylic acid; 8-Methyl-2-carboxy-4-chromone; 8-Methylcoumarilic acid; 38243-78-6
EINECS	Contact for details

Quality Control

Our 8-Methyl-4-oxo-4H-chromene-2-carboxylic acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, from research (≥95%) to pharmaceutical intermediate (≥98%) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.