Description

2-Chloro-1-Ethoxy-4-Isocyanatobenzene is a specialized aromatic isocyanate intermediate of significant importance in advanced organic synthesis. Its core value lies in its dual functional groups—the reactive isocyanate and the chloro-ethoxy-substituted benzene ring—which enable precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key building block for creating novel active ingredients and functional materials.

Application

• Primary building block for the synthesis of novel pharmaceutical intermediates, particularly in the development of targeted therapies.
• Key starting material in the production of advanced agrochemicals, including herbicides and fungicides with specific modes of action.
• Intermediate for the synthesis of specialty polymers and resins, where it can impart specific chemical resistance or reactivity.
• Used in research and development for creating custom chemical entities and molecular probes in medicinal chemistry.
• Precursor in the manufacture of dyes and pigments with enhanced performance characteristics.
• Employed in the synthesis of liquid crystal materials and other advanced electronic chemicals.

Basic Information

Product Name	2-Chloro-1-Ethoxy-4-Isocyanatobenzene
CAS No.	38241-51-9
Molecular Formula	C9H8ClNO2
Molecular Weight	197.62 g/mol
Synonyms	4-Isocyanato-2-chloro-1-ethoxybenzene; 2-Chloro-4-isocyanato-1-ethoxybenzene; 1-Chloro-2-ethoxy-4-isocyanatobenzene; 2-Chlorophenetole-4-isocyanate; 4-Isocyanato-2-chlorophenetole; 2-Chloro-1-ethoxy-4-isocyanato-benzene; Benzene, 2-chloro-1-ethoxy-4-isocyanato-; 1-Ethoxy-2-chloro-4-isocyanatobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1-Ethoxy-4-Isocyanatobenzene is produced under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for research and industrial-scale applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under a dry, inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and sources of ignition. Isolate from moisture, amines, alcohols, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.