Description

4'-Iodophenyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-B-D-Glucopyranoside is a sophisticated, high-purity glycosylation building block and a key intermediate in synthetic carbohydrate chemistry. This compound is critical for researchers and manufacturers developing novel glycoconjugates, glycomimetics, and bioactive molecules for pharmaceutical and diagnostic applications. Its precise structure, featuring a protected glucosamine core and an iodophenyl aglycone, makes it an essential reagent for targeted synthesis in medicinal chemistry and glycobiology research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex glycoconjugates and glycomimetic drugs targeting various diseases.
• Glycobiology Research: Used in enzymatic and chemical glycosylation studies to understand carbohydrate-protein interactions and cell signaling pathways.
• Diagnostic Probe Development: Serves as a precursor for radiolabeled (e.g., with I-125) or fluorescently tagged carbohydrate probes for imaging and detection.
• Chemical Biology Tool: Employed in the synthesis of activity-based probes (ABPs) and other chemical tools to study glycosidases and glycosyltransferases.
• Carbohydrate Library Synthesis: A valuable starting material for creating diverse libraries of oligosaccharides and neoglycoconjugates for screening.
• Academic & Industrial R&D: Fundamental reagent for exploratory research in synthetic organic chemistry focused on carbohydrate derivatives.

Basic Information

Product Name	4'-Iodophenyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-B-D-Glucopyranoside
CAS No.	38229-75-3
Molecular Formula	C20H24INO9
Molecular Weight	549.31 g/mol
Synonyms	2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl 4-iodophenyl ether; 4-Iodophenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; N-Acetyl-3,4,6-tri-O-acetyl-β-D-glucosaminyl 4-iodophenyl ether; 4-Iodophenyl β-D-GlcNAc(Ac)3; p-Iodophenyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside; Glycosylation donor 38229-75-3; Protected N-acetylglucosamine iodide derivative
EINECS	Contact for details

Quality Control

Our 4'-Iodophenyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-B-D-Glucopyranoside is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee the material meets your specific research-grade or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.