Description

1-Cyclobutene-1-Carboxylic Acid, 2-[(Methylamino)Carbonyl]- is a specialized organic compound featuring a cyclobutene ring fused with a carboxylic acid and a methylaminocarbonyl substituent, making it a valuable, high-purity building block for advanced synthesis. This compound is critical for research and development in pharmaceutical chemistry, where it serves as a key intermediate for constructing novel molecular scaffolds with potential biological activity. It is primarily sought after by fine chemical manufacturers, pharmaceutical R&D laboratories, and agrochemical innovators engaged in the synthesis of complex, target-specific molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the creation of novel herbicides or fungicides, where the cyclobutene core can contribute to unique modes of action and improved environmental profiles.
• Material Science Research: Serves as a precursor for specialty polymers or liquid crystals, where its rigid, strained ring structure can impart desirable thermal or optical properties.
• Academic & Industrial R&D: Employed in methodological chemistry studies, such as cycloaddition reactions or as a substrate for developing new catalytic processes in organic synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex heterocyclic carboxylic acid derivatives.

Basic Information

Product Name	1-Cyclobutene-1-Carboxylic Acid, 2-[(Methylamino)Carbonyl]-
CAS No.	38197-76-1
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	2-(Methylcarbamoyl)cyclobut-1-ene-1-carboxylic acid; N-Methyl-1,2-cyclobutenedicarboximide precursor; 1-Cyclobutene-1,2-dicarboxylic acid 2-methylamide; Methyl 1-cyclobutene-1-carboxylate-2-carboxamide derivative; Cyclobut-1-ene-1-carboxylic acid, 2-[(methylamino)carbonyl]-; 38197-76-1; 1-Cyclobutene-1,2-dicarboxylic acid mono-N-methylamide
EINECS	Contact for details

Quality Control

Our production of 1-Cyclobutene-1-Carboxylic Acid, 2-[(Methylamino)Carbonyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with cGMP and ISO 9001 standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require desiccant or storage under an inert atmosphere for long-term preservation to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.