Description

(6S)-4-Methoxy-6α-(3-Hydroxy-4-Methoxyphenethyl)-5,6-Dihydro-2H-Pyran-2-One CAS NO 38146-59-7 is a high-purity, synthetic organic compound belonging to the dihydropyranone class, valued for its role as a key chiral intermediate in advanced pharmaceutical synthesis. Its complex stereochemistry and functional groups make it a critical building block for developing active pharmaceutical ingredients (APIs) with specific therapeutic profiles. This compound is essential for research and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures due to its defined (6S) configuration.
• Medicinal Chemistry Research: Employed in R&D laboratories for the discovery and optimization of new therapeutic agents, particularly in areas requiring specific stereochemistry.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Fine Chemical Synthesis: Acts as a precursor for other specialty chemicals and advanced materials requiring its unique dihydropyranone core.

Basic Information

Product Name	(6S)-4-Methoxy-6α-(3-Hydroxy-4-Methoxyphenethyl)-5,6-Dihydro-2H-Pyran-2-One
CAS No.	38146-59-7
Molecular Formula	C₁₇H₂₂O₅
Molecular Weight	306.36 g/mol
Synonyms	(6S)-4-Methoxy-6-(3-Hydroxy-4-methoxyphenethyl)-5,6-dihydro-2H-pyran-2-one; (6S)-6-(3-Hydroxy-4-methoxyphenethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one; 4-Methoxy-6α-(3-hydroxy-4-methoxyphenethyl)-5,6-dihydro-2H-pyran-2-one, (6S)-; 38146-59-7; (6S)-Dihydropyranone derivative; Chiral dihydropyranone intermediate; (S)-enantiomer of the specified methoxyphenethyl dihydropyranone.
EINECS	Contact for details

Quality Control

Our (6S)-4-Methoxy-6α-(3-Hydroxy-4-Methoxyphenethyl)-5,6-Dihydro-2H-Pyran-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can support development and regulatory needs with comprehensive documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.