Description

Phenylzinc Bromide is an organozinc reagent, a versatile and highly reactive intermediate for the formation of carbon-carbon bonds. Its primary value lies in its utility as a phenyl anion equivalent in cross-coupling and nucleophilic addition reactions, offering chemists a powerful tool for constructing complex aromatic frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise organic synthesis is critical for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing phenyl groups into target molecules during the research and development of new drug candidates.
• Negishi Cross-Coupling Reactions: Used as a transmetalation agent with palladium catalysts to form biaryl and other aromatic compounds.
• Nucleophilic Addition to Carbonyls: Employed for the addition of phenyl groups to aldehydes, ketones, and imines.
• Agrochemical Manufacturing: Intermediate in the synthesis of herbicides, fungicides, and other crop protection agents containing phenyl substituents.
• Materials Science Research: Building block for creating organic semiconductors, liquid crystals, and polymers with specific aromatic properties.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing for specialty aromatic compounds.

Basic Information

Product Name	Phenylzinc Bromide
CAS No.	38111-44-3
Molecular Formula	C6H5BrZn
Molecular Weight	202.39 g/mol
Synonyms	Bromophenylzinc; Phenylzinc bromide solution; Zinc, bromophenyl-; (Phenyl)zinc bromide; Bromo(phenyl)zinc; Phenyl zinc bromide; Phenylzinc bromide, 0.5M in THF
EINECS	Contact for details

Quality Control

Our Phenylzinc Bromide is produced under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, concentration (typically as a solution in THF), and the absence of significant protic impurities. A comprehensive Certificate of Analysis (COA) detailing assay, NMR characterization, and titration results is provided with every shipment to support your quality assurance and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a highly volatile, hygroscopic (moisture-sensitive), and easily oxidized (store under inert atmosphere) reagent, it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, typical recommended storage temperature is 2-8°C. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Concentration (Titration)	0.5 M in THF (or as specified)
Assay (Zn content)	≥ 95%
Water Content (Karl Fischer)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.