Description

Diethoxy-[(5-Methoxy-1,3,4-Thiadiazol-2-Yl)Methylsulfanyl]-Sulfanylide Ne-Phosphorane is a specialized organophosphorus reagent featuring a unique thiadiazole moiety. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the construction of complex heterocyclic systems and active pharmaceutical ingredients (APIs). It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for novel compound libraries and process development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those containing 1,3,4-thiadiazole cores, which are known for diverse biological activities.
• Agrochemical Synthesis: Used in the research and production of new-generation herbicides, fungicides, and insecticides that leverage the thiadiazole scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine-based ligands used in transition metal catalysis for fine chemical manufacturing.
• Material Science Research: Employed in the development of organic electronic materials and polymers where the introduction of sulfur and nitrogen heterocycles can modify electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthetic routes under cGMP conditions where applicable.

Basic Information

Product Name	Diethoxy-[(5-Methoxy-1,3,4-Thiadiazol-2-Yl)Methylsulfanyl]-Sulfanylide Ne-Phosphorane
CAS No.	38090-82-3
Molecular Formula	C8H15N2O3PS3
Molecular Weight	314.38 g/mol
Synonyms	Diethoxy[(5-methoxy-1,3,4-thiadiazol-2-yl)methylsulfanyl]sulfanylidene-λ5-phosphane; (5-Methoxy-1,3,4-thiadiazol-2-yl)methyl diethoxyphosphinodithioate; Ne-Phosphorane, diethoxy[(5-methoxy-1,3,4-thiadiazol-2-yl)methylthio]thioxo-; Phosphorodithioic acid, (5-methoxy-1,3,4-thiadiazol-2-yl)methyl ester, O,O-diethyl ester; CAS 38090-82-3
EINECS	Contact for details

Quality Control

Our Diethoxy-[(5-Methoxy-1,3,4-Thiadiazol-2-Yl)Methylsulfanyl]-Sulfanylide Ne-Phosphorane is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support development projects requiring compliance with various pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) and handle it in a moisture-controlled environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.