Description

1-[m-(Trifluoromethyl)Phenyl]-2-Propanone o-[2-(Diethylamino)Ethyl]Oxime is a specialized organic compound featuring a trifluoromethylphenyl group and a diethylaminoethyl oxime moiety. This unique structure makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its specific functional groups are leveraged to introduce key pharmacophores or modify physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, or insecticides, where the trifluoromethyl group is a common feature for improving efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile synthon in academic and industrial laboratories for exploring new synthetic methodologies and creating libraries of compounds for biological screening.
• Ligand and Catalyst Precursor: The oxime and amine functionalities can be utilized to develop novel ligands for metal catalysis or as precursors for more complex chelating agents.
• Material Science Applications: Potential use in the synthesis of specialty polymers or advanced materials where fluorinated aromatic units impart specific properties like chemical resistance or altered surface energy.

Basic Information

Product Name	1-[m-(Trifluoromethyl)Phenyl]-2-Propanone o-[2-(Diethylamino)Ethyl]Oxime
CAS No.	38060-02-5
Molecular Formula	C16H21F3N2O
Molecular Weight	314.35 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-2-propanone O-[2-(diethylamino)ethyl]oxime; m-Trifluoromethylphenylacetone O-(2-diethylaminoethyl)oxime; 3'-Trifluoromethylphentermone oxime; 1-(3-Trifluoromethylphenyl)-2-propanone O-(2-(diethylamino)ethyl)oxime; α-Methyl-3-(trifluoromethyl)benzenecetaldehyde O-(2-(diethylamino)ethyl)oxime; 38060-02-5; Phentermone derivative oxime
EINECS	Contact for details

Quality Control

Our 1-[m-(Trifluoromethyl)Phenyl]-2-Propanone o-[2-(Diethylamino)Ethyl]Oxime is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity, typically including HPLC for assay, GC for residual solvents, and IR/NMR for structural confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems support development and cGMP manufacturing requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.