Description

3β,16β-Bis(Trimethylsilyloxy)-5α-Androstane is a high-purity, silylated steroid derivative, primarily utilized as a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in providing a protected functional group strategy, enabling precise and efficient chemical transformations in complex organic syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly those focused on developing novel steroid-based therapeutics, hormone analogs, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D laboratories for exploring new synthetic pathways and creating novel steroid derivatives.
• Hormone Analog Synthesis: Serves as a precursor in the development of modified androstane structures with potential therapeutic activity.
• Fine Chemical Production: Employed in the manufacture of high-value, specialized chemicals for advanced material science and biotechnology applications.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in chromatographic analysis.

Basic Information

Product Name	3β,16β-Bis(Trimethylsilyloxy)-5α-Androstane
CAS No.	37977-24-5
Molecular Formula	C25H48O2Si2
Molecular Weight	452.82 g/mol
Synonyms	5α-Androstane-3β,16β-diol bis(trimethylsilyl) ether; 3β,16β-Bis-O-(trimethylsilyl)-5α-androstane; 5α-Androstane-3β,16β-diyl bis(oxy)bis(trimethylsilane); Androstane-3β,16β-diol, bis(trimethylsilyl) ether; 3β,16β-Di(trimethylsiloxy)-5α-androstane; 37977-24-5; 5α-Androstane-3β,16β-diol, 3,16-bis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our 3β,16β-Bis(Trimethylsilyloxy)-5α-Androstane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.