Description

3-(4-Nitro-Phenylcarbamoyl)-Acrylic Acid is a specialized nitroaromatic acrylic acid derivative, serving as a versatile chemical intermediate for advanced synthesis. Its molecular structure, featuring both a reactive acrylic acid moiety and a nitro-substituted phenylcarbamoyl group, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought by research and development laboratories, pharmaceutical manufacturers, and agrochemical producers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its nitroaromatic functionality.
• Dye and Pigment Synthesis: Serves as a precursor for azo dyes and other complex colorants due to its aromatic nitro group and polymerizable acrylic unit.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and synthesizing complex heterocyclic compounds.
• Material Science: Investigated for use in advanced materials, such as organic semiconductors or nonlinear optical materials.

Basic Information

Product Name	3-(4-Nitro-Phenylcarbamoyl)-Acrylic Acid
CAS No.	37904-21-5
Molecular Formula	C10H8N2O5
Molecular Weight	236.18 g/mol
Synonyms	3-[(4-Nitrophenyl)carbamoyl]acrylic acid; 2-Propenoic acid, 3-[(4-nitrophenyl)amino]-3-oxo-; (E)-3-((4-Nitrophenyl)carbamoyl)acrylic acid; 4-Nitro-N-acrylylaniline-3-carboxylic acid; Acrylic acid, 3-(4-nitrophenylcarbamoyl)-; 3-Carboxyacryloyl-4-nitroanilide; N-(4-Nitrophenyl)maleamic acid (related structure); 37904-21-5
EINECS	Contact for details

Quality Control

Our production of 3-(4-Nitro-Phenylcarbamoyl)-Acrylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay value. Our quality system is designed to meet the rigorous demands of research and cGMP-grade manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.