Description

1,3-Cyclobutanedione, 2,4-Dichloro- is a high-purity, halogenated diketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex heterocyclic systems and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex, biologically active heterocyclic cores, such as fused pyrazoles or thiazoles, in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require specific halogenated diketone motifs.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in coordination chemistry and catalysis, particularly where electron-withdrawing groups are beneficial.
• Polymer and Material Science: Employed in the synthesis of monomers for specialty polymers, including polyimides or photosensitive resins, where the dichloro-substituted cyclobutane ring can impart unique thermal or optical properties.
• Organic Electronic Materials: Investigated as a building block for electron-accepting units in the design of organic semiconductors and non-fullerene acceptors for photovoltaic applications.
• Cross-Coupling Reactions: The chlorine atoms provide handles for further functionalization via metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille), enabling rapid diversification of the molecular scaffold.

Basic Information

Product Name	1,3-Cyclobutanedione, 2,4-Dichloro-
CAS No.	37873-66-8
Molecular Formula	C4H2Cl2O2
Molecular Weight	152.96 g/mol
Synonyms	2,4-Dichloro-1,3-cyclobutanedione; 2,4-Dichlorocyclobutane-1,3-dione; 1,3-Cyclobutanedione, 2,4-dichloro-; Dichlorocyclobutanedione; NSC 163063
EINECS	Contact for details

Quality Control

Our 1,3-Cyclobutanedione, 2,4-Dichloro- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.