Description

1-Phenylcyclobutanecarboxylic Acid is a versatile organic building block featuring a cyclobutane ring fused with a phenylcarboxylic acid moiety. This unique structure makes it a valuable intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is sought after by R&D chemists and process development scientists for creating novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging its rigid bicyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals due to its aromatic and alicyclic components.
• Academic & Industrial R&D: A fundamental reagent in organic chemistry laboratories for method development and exploring new chemical spaces.

Basic Information

Product Name	1-Phenylcyclobutanecarboxylic Acid
CAS No.	37828-19-6
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	Cyclobutanecarboxylic acid, 1-phenyl-; 1-Phenylcyclobutane-1-carboxylic acid; α-Phenylcyclobutanecarboxylic acid; 1-Carboxy-1-phenylcyclobutane; PCBA; 1-Phenyl-1-cyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Phenylcyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.