Description

Poly(Oxy-1,2-Ethanediyl), .Alpha.-(2-Carboxybenzoyl)-.Omega.-[(2-Carboxybenzoyl)Oxy]- is a specialized functionalized polyethylene glycol (PEG) derivative, where both termini are modified with phthalic acid moieties. This unique bifunctional structure provides enhanced reactivity and compatibility, making it a valuable intermediate for advanced material synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, polymer, and specialty chemical industries for applications requiring precise molecular architecture and controlled functionalization.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, polymer-drug conjugates, and biodegradable polymers for controlled drug delivery systems.
• Polymer Modification: Acts as a chain extender or cross-linking agent to introduce carboxyl groups into polyesters, polyurethanes, and other polymers, altering their solubility and bio-properties.
• Surface Functionalization: Employed to modify the surface of nanoparticles, quantum dots, or medical devices to improve hydrophilicity, biocompatibility, and targeting capabilities.
• Specialty Chemical Synthesis: Serves as a key building block for creating complex dendrimers, hydrogels, and other advanced functional materials.
• Adhesive & Coating Formulations: Used as a component to enhance adhesion, flexibility, and chemical resistance in high-performance coatings and adhesives.
• Analytical & Diagnostic Reagents: Can be utilized in the development of biosensors, assay components, and separation media due to its derivatization potential.

Basic Information

Product Name	Poly(Oxy-1,2-Ethanediyl), .Alpha.-(2-Carboxybenzoyl)-.Omega.-[(2-Carboxybenzoyl)Oxy]-
CAS No.	37684-52-9
Molecular Formula	C18H14O8 • (C2H4O)n (n varies by PEG chain length)
Molecular Weight	Variable, dependent on PEG chain length (n). Contact for details on specific grades.
Synonyms	α,ω-Bis(2-carboxybenzoyl) poly(ethylene glycol); PEG-diphthalate; Polyethylene glycol bis(2-carboxybenzoate); Bis(2-carboxybenzoyl) PEG; Phthalic acid, bis[2-(polyethylene glycol) ester]; Poly(ethylene glycol) bis(o-carboxybenzoyl) ether; PEG-dicarboxyphthalate; Functionalized PEG derivative
EINECS	Contact for details

Quality Control

Our production of Poly(Oxy-1,2-Ethanediyl), .Alpha.-(2-Carboxybenzoyl)-.Omega.-[(2-Carboxybenzoyl)Oxy]- adheres to strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure consistency in molecular weight distribution, functional group content, and purity. Certificates of Analysis (COA) detailing key parameters such as assay, acid value, and residual solvents are available upon request. We support custom synthesis and can tailor specifications to meet specific GMP or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). To prevent degradation and clumping, the container must be kept tightly sealed in a dry environment, ideally with desiccant. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Acid Value	Specified per grade
Average Molecular Weight (GPC)	As per customer requirement (e.g., 600, 1000, 2000 Da)
Moisture Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.