Description

Sennoside D CAS NO 37271-17-3 is a purified, high-purity anthraquinone glycoside compound, serving as a critical reference standard and active pharmaceutical ingredient (API). This compound is essential for ensuring the quality, potency, and consistency of pharmaceutical formulations and botanical extracts. It is primarily required by manufacturers and research institutions in the pharmaceutical, nutraceutical, and analytical chemistry sectors for development, quality control, and standardization purposes.

Application

• Pharmaceutical Reference Standard: Used as a primary chemical reference material for the identification and quantification of sennosides in bulk drugs and finished formulations.
• Active Pharmaceutical Ingredient (API): A key component in the manufacture of prescription and over-the-counter laxative medications.
• Herbal Extract Standardization: Employed to standardize senna leaf and pod extracts to a defined sennoside content for consistent therapeutic effect.
• Analytical Research & Method Development: Critical for developing and validating analytical methods such as HPLC, UPLC, and TLC in quality control laboratories.
• Pharmacological Studies: Used in preclinical and clinical research to study the efficacy, metabolism, and safety profile of sennoside compounds.
• Dietary Supplement Manufacturing: Incorporated into natural health products requiring standardized senna components.

Basic Information

Product Name	Sennoside D
CAS No.	37271-17-3
Molecular Formula	C42H38O20
Molecular Weight	862.75 g/mol
Synonyms	Sennoside D; 6,6'-Dimer of Aloe-emodin-8-glucoside; Rhein-8-glucoside dimer; Cassioside; 5,5'-Dihydroxy-2,2'-dimethyl-[4,4'-bianthracene]-9,9',10,10'-tetrone 8,8'-di-β-D-glucopyranoside; (R,R)-Sennoside D; Sennidin D glycoside
EINECS	Contact for details

Quality Control

Our Sennoside D is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) with detailed chromatograms and test results are provided to guarantee traceability, consistency, and compliance with relevant pharmacopeial standards (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.