Description

5-Bromo-6-(2-Nitro-1-Propen-1-Yl)-1,3-Benzodioxole is a specialized organic intermediate featuring a benzodioxole core functionalized with bromo and nitroalkene substituents. This unique molecular architecture makes it a valuable building block for synthesizing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the benzodioxole moiety can contribute to biological activity.
• Organic Synthesis Building Block: Serves as a versatile electrophile or Michael acceptor in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic addition reactions due to its reactive nitroalkene group.
• Material Science Research: Investigated as a monomer or functional component in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular pathways.

Basic Information

Product Name	5-Bromo-6-(2-Nitro-1-Propen-1-Yl)-1,3-Benzodioxole
CAS No.	37162-74-6
Molecular Formula	C₁₀H₈BrNO₄
Molecular Weight	286.08 g/mol
Synonyms	5-Bromo-6-(2-nitroprop-1-en-1-yl)-1,3-benzodioxole; 1,3-Benzodioxole, 5-bromo-6-(2-nitro-1-propen-1-yl)-; 5-Bromo-6-(2-nitroprop-1-enyl)-1,3-benzodioxole; 6-(2-Nitroprop-1-enyl)-5-bromo-1,3-benzodioxole; 5-Bromo-6-(2-nitropropenyl)-1,3-benzodioxole
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-(2-Nitro-1-Propen-1-Yl)-1,3-Benzodioxole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.