Description

4-Carboxy-2,2,6,6-Tetramethylpiperidine 1-Oxyl is a stable nitroxide radical, widely recognized as a key intermediate and spin label in advanced chemical synthesis and research. This compound matters for its exceptional utility as a polymerization inhibitor, a spin-trapping agent in electron paramagnetic resonance (EPR) spectroscopy, and a building block for functional materials. It is critically needed by R&D laboratories, polymer manufacturers, and pharmaceutical developers working on radical chemistry, material science, and as a precursor for hindered amine light stabilizers (HALS).

Application

• Polymerization Inhibitor: Used to control and inhibit free-radical polymerization during the storage and processing of monomers like styrene and acrylics.
• Spin Labeling & EPR Studies: Serves as a stable radical probe for investigating molecular dynamics, protein structures, and membrane properties via Electron Paramagnetic Resonance spectroscopy.
• Precursor for HALS (Hindered Amine Light Stabilizers): A crucial intermediate in the synthesis of high-performance light stabilizers for plastics, coatings, and polymers to prevent UV degradation.
• Organic Synthesis & Catalysis: Employed as a catalyst or mediator in oxidation reactions and the synthesis of complex organic molecules.
• Biomedical Research: Utilized as a spin trap to detect and quantify short-lived free radicals in biological systems and study oxidative stress.
• Functional Material Development: Incorporated into the design of magnetic materials, molecular switches, and advanced polymers with specific electronic properties.

Basic Information

Product Name	4-Carboxy-2,2,6,6-Tetramethylpiperidine 1-Oxyl
CAS No.	37149-18-1
Molecular Formula	C10H18NO3
Molecular Weight	200.26 g/mol
Synonyms	4-Carboxy-TEMPO; 4-Carboxy-2,2,6,6-tetramethylpiperidin-1-oxyl; 4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl; 4-Carboxy-TEMPO radical; 4-Carboxy-2,2,6,6-tetramethyl-1-piperidinyloxy; 4-Carboxy-2,2,6,6-tetramethylpiperidine-1-oxyl free radical; 4-Carboxy-2,2,6,6-tetramethylpiperidinyloxy; 4-Carboxy-TEMPOL (less common)
EINECS	Contact for details

Quality Control

Our 4-Carboxy-2,2,6,6-Tetramethylpiperidine 1-Oxyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and EPR for radical content verification, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Radical Content (EPR)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.