Description

1-Chloro-4-Ethoxybutane is a versatile halogenated ether intermediate of significant interest in organic synthesis. Its bifunctional structure, featuring both an ether linkage and a reactive chloroalkyl group, makes it a valuable building block for the creation of more complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as alkylation and the synthesis of functionalized ethers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific ether functionalities.
• Specialty Polymer Modifier: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions to introduce the 4-ethoxybutyl moiety into target structures.
• Ligand and Catalyst Preparation: Useful for synthesizing chelating ligands or modifying catalyst surfaces in coordination chemistry.
• Flavor and Fragrance Industry: May be used as an intermediate in the synthesis of certain aroma chemicals.

Basic Information

Product Name	1-Chloro-4-Ethoxybutane
CAS No.	36865-43-7
Molecular Formula	C6H13ClO
Molecular Weight	136.62 g/mol
Synonyms	4-Ethoxybutyl chloride; Butane, 1-chloro-4-ethoxy-; 1-Chloro-4-ethoxy-butane; 4-Chlorobutyl ethyl ether; Ethyl 4-chlorobutyl ether; NSC 88487; γ-Ethoxybutyl chloride
EINECS	253-235-4

Quality Control

Our 1-Chloro-4-Ethoxybutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC analysis for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for extended stability, although the product is typically stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.425 - 1.435
Density (20°C)	0.96 - 1.00 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.