Description

Silybin (Mixture Of Silybin A And Silybin B) is a standardized flavonolignan complex primarily derived from the milk thistle plant (*Silybum marianum*). This compound is valued for its potent hepatoprotective and antioxidant properties, making it a critical active pharmaceutical ingredient (API) and nutraceutical component. It is essential for manufacturers in the pharmaceutical, dietary supplement, and cosmeceutical industries seeking a high-purity, bioactive ingredient for liver support formulations.

Application

• Pharmaceutical Active Ingredient (API): Core component in prescription and over-the-counter (OTC) medications for liver disorders, including toxin-induced liver damage, alcoholic liver disease, and supportive therapy for chronic hepatitis.
• Dietary Supplements & Nutraceuticals: Key ingredient in capsules, tablets, and liquid extracts marketed for liver detoxification, antioxidant support, and general hepatic health.
• Cosmeceuticals: Incorporated into advanced skincare formulations for its anti-inflammatory and antioxidant benefits, helping to protect skin from environmental stressors and support skin vitality.
• Veterinary Pharmaceuticals: Used in veterinary medicines to support liver function in companion animals and livestock.
• Research & Development: Serves as a reference standard and key material in pharmacological, toxicological, and biochemical research exploring hepatoprotection and flavonoid mechanisms.

Basic Information

Product Name	Silybin (Mixture Of Silybin A And Silybin B)
CAS No.	36804-17-8
Molecular Formula	C25H22O10
Molecular Weight	482.44 g/mol
Synonyms	Silibinin; Silymarin I; Silybin; Silybinin; Silybum substance E6; Legalon; Silibinin A and B mixture; 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin-8-one
EINECS	253-257-5

Quality Control

Our Silybin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. It is typically manufactured to meet relevant standards for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment, and we support customer-specific validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Complies with reference standard
Identification (IR)	Complies with reference spectrum
Assay (HPLC)	≥ 98.0% (Total Silybin A and B)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Total Aerobic Microbial Count	≤ 1000 cfu/g
Total Yeast & Mold Count	≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.