Description

4-Cyanothiophenol is a versatile sulfur-containing aromatic compound featuring both a cyano and a thiol functional group. This unique structure makes it a valuable building block in organic synthesis, particularly for the creation of complex heterocycles and functional materials. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from catalyst ligands to polymer modification.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thioether or heterocyclic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophenol moiety is integral to biological activity.
• Ligand for Catalysis: Serves as a building block for creating specialized ligands in transition metal catalysis for cross-coupling and other organic transformations.
• Polymer Modification: Employed as a chain-transfer agent or functional monomer to introduce sulfur and cyano groups into polymers, altering their physical and chemical properties.
• Material Science Research: Used in the development of self-assembled monolayers (SAMs) and organic electronic materials due to its ability to bind to metal surfaces.
• Chemical Research & Development: A versatile reagent for constructing sulfur-nitrogen containing heterocycles like benzothiazoles and thiazoles in academic and industrial labs.

Basic Information

Product Name	4-Cyanothiophenol
CAS No.	36801-01-1
Molecular Formula	C7H5NS
Molecular Weight	135.19 g/mol
Synonyms	4-Mercaptobenzonitrile; p-Cyanobenzenethiol; 4-Sulfanylbenzonitrile; p-Thiocyanophenol; Benzonitrile, 4-mercapto-; 4-Cyanobenzenethiol; p-Mercaptobenzonitrile; 1-Cyano-4-mercaptobenzene
EINECS	253-204-5

Quality Control

Our 4-Cyanothiophenol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.