Description

2-(tert-Butylsulfonyl)Acetonitrile is a versatile organosulfur building block characterized by its reactive nitrile group and electron-withdrawing sulfonyl moiety. This compound is essential for the synthesis of complex heterocycles and functionalized molecules, offering chemists a critical handle for carbon-carbon bond formation and further derivatization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for constructing sulfonamide-based pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific sulfonyl acetonitrile backbones.
• Organic Synthesis Reagent: Serves as a versatile building block in palladium-catalyzed cross-coupling reactions, cyanoalkylation, and other C-H functionalization processes.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a precursor for functional polymers and advanced materials with tailored electronic properties.

Basic Information

Product Name	2-(tert-Butylsulfonyl)Acetonitrile
CAS No.	36635-64-0
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	2-(tert-Butylsulfonyl)acetonitrile; (tert-Butylsulfonyl)acetonitrile; 2-(tert-Butylsulfonyl)ethanenitrile; Acetonitrile, 2-[(1,1-dimethylethyl)sulfonyl]-; 2-(tert-Butanesulfonyl)acetonitrile; 2-(t-Butylsulfonyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(tert-Butylsulfonyl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.