Description

Acetic Acid, [(1,1-Dimethylethyl)Sulfonyl]- is a specialized organosulfur compound that serves as a valuable building block and reagent in advanced synthetic chemistry. This compound is particularly significant for introducing the tert-butylsulfonyl (Bus) protecting group, which offers enhanced stability under various reaction conditions compared to other sulfonyl groups. It is primarily needed by research and development laboratories, pharmaceutical intermediates manufacturers, and fine chemical producers engaged in the synthesis of complex molecules, peptides, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent for the introduction of the tert-butylsulfonyl (Bus) protecting group in multi-step synthetic routes for novel drug candidates and APIs.
• Peptide Chemistry: Employed in the protection of amino acid side chains, particularly for amines, to prevent unwanted side reactions during peptide coupling and deprotection sequences.
• Agrochemical Research: Serves as a precursor or intermediate in the development of new herbicides, fungicides, and insecticides with tailored properties.
• Material Science: Utilized in the synthesis of specialty polymers and functional materials where the sulfonyl moiety imparts specific chemical or physical characteristics.
• Organic Synthesis Reagent: Acts as a versatile electrophile or sulfonylation agent in various carbon-sulfur and carbon-heteroatom bond-forming reactions.
• Chemical Biology Probes: Applied in the design and synthesis of molecular probes for studying enzyme mechanisms and protein function.

Basic Information

Product Name	Acetic Acid, [(1,1-Dimethylethyl)Sulfonyl]-
CAS No.	36610-02-3
Molecular Formula	C6H12O4S
Molecular Weight	180.22 g/mol
Synonyms	tert-Butylsulfonylacetic Acid; 2-[(tert-Butylsulfonyl)]acetic Acid; Bus-AcOH; (tert-Butanesulfonyl)acetic Acid; 2-(tert-Butylsulfonyl)ethanoic Acid; Acetic Acid, 2-(tert-Butylsulfonyl)-; 2-(tert-Butylsulfonyl)acetic Acid; NSC 163063
EINECS	Contact for details

Quality Control

Our Acetic Acid, [(1,1-Dimethylethyl)Sulfonyl]- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.