Description

2-(4-Bromophenoxy)Tetrahydro-2H-Pyran is a versatile brominated aromatic ether and a protected form of 4-bromophenol, where the hydroxyl group is masked with a tetrahydropyranyl (THP) protecting group. This compound is of significant value in synthetic organic chemistry, particularly in multi-step synthesis where selective deprotection is required. It serves as a crucial key intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the construction of complex molecules with high precision.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly where the bromophenol moiety is a key structural element.
• Agrochemical Synthesis: Serves as a building block for herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal-catalyzed coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Polymer and Material Science: Acts as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and advanced organic materials.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for constructing complex aromatic ethers and exploring new synthetic methodologies.
• Fine Chemical Production: Utilized in the manufacture of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-(4-Bromophenoxy)Tetrahydro-2H-Pyran
CAS No.	36603-49-3
Molecular Formula	C11H13BrO2
Molecular Weight	257.13 g/mol
Synonyms	4-Bromophenyl tetrahydropyran-2-yl ether; 2-(4-Bromophenoxy)oxane; THP-protected 4-bromophenol; 4-Bromophenol tetrahydropyranyl ether; 2H-Pyran, 2-(4-bromophenoxy)tetrahydro-; 4-Bromophenyl 2-tetrahydropyranyl ether; 2-(p-Bromophenoxy)tetrahydropyran; Bromophenoxy THP ether
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenoxy)Tetrahydro-2H-Pyran is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.