Description

3-Azetidinecarboxylic Acid is a versatile heterocyclic building block and a key intermediate in organic synthesis. This compound is valued for its constrained, four-membered ring structure, which is crucial for modulating the conformational and pharmacokinetic properties of target molecules. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials research sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of protease inhibitors, β-lactam analogs, and other bioactive molecules targeting neurological and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators with enhanced activity profiles.
• Peptidomimetics & Drug Design: Serves as a proline bioisostere to introduce conformational rigidity into peptide chains, improving metabolic stability and receptor selectivity.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Acts as a monomer or functionalizing agent for creating polymers with unique thermal and mechanical properties.
• Chemical Biology Research: Utilized as a tool compound for studying enzyme mechanisms and protein-protein interactions.

Basic Information

Product Name	3-Azetidinecarboxylic Acid
CAS No.	36476-78-5
Molecular Formula	C4H7NO2
Molecular Weight	101.10 g/mol
Synonyms	Azetidine-3-carboxylic Acid; 3-Carboxyazetidine; (Azetidin-3-yl)carboxylic Acid; 3-Azetidinecarboxylic Acid; Azetidine-3-carboxylic Acid; 3-Azetidinecarboxylic Acid; Azetidine-3-carboxylic Acid; 3-Carboxyazetidine
EINECS	Contact for details

Quality Control

Our 3-Azetidinecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and research environments where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.