Description

1,2-Dibromo-3,4,5,6-Tetramethylbenzene is a highly functionalized, multi-substituted aromatic bromine compound, serving as a critical advanced intermediate in organic synthesis. Its value lies in the precise positioning of bromine atoms and methyl groups, which provides unique reactivity and steric properties for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, custom-tailored building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring sterically hindered, brominated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the tetramethylbenzene structure imparts specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a backbone for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, or metal-organic frameworks (MOFs) due to its rigid, multi-substituted structure.
• Chemical Research & Development: A versatile building block for Suzuki, Stille, and other cross-coupling reactions to create complex poly-substituted aromatic systems.
• Flame Retardant Synthon: Acts as a brominated intermediate in the development of specialized, high-performance flame retardant additives for polymers.

Basic Information

Product Name	1,2-Dibromo-3,4,5,6-Tetramethylbenzene
CAS No.	36321-73-0
Molecular Formula	C10H12Br2
Molecular Weight	307.99 g/mol
Synonyms	1,2-Dibromo-3,4,5,6-tetramethylbenzene; 3,4,5,6-Tetramethyl-1,2-dibromobenzene; Durene, 1,2-dibromo-; 1,2-Dibromodurene; 1,2-Dibromo-3,4,5,6-tetramethyl-benzene; Benzene, 1,2-dibromo-3,4,5,6-tetramethyl-
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-3,4,5,6-Tetramethylbenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.